International Conference on Carbonic Anhydrase 2012

Greetings from the president,
The 9th International Conference on Carbonic Anhydrase (CA) will be held in Antalya, Turkey, between April 11-15, 2012. This is now a traditional event taking place each three years, and as in the last meetings, it will bring together researchers active in this field from all over the world.

A high number of well-known personalities in the CA research will participate, and some of them are in the organizing committee shown below. Professors, researchers, students and especially young researchers active in the CA research in the last years are heartedly invited to participate. Indeed, although we shall follow the format of the last several meetings, a special session dedicated to presentations from young researchers will be held.

The final sessions for this multidisciplinary event, are outlined below:

1.Comparative aspects of new CA families and isozymes
2.Regulation of expression of CA isoforms
3.CAs as drug and diagnostic targets
4.Roles of CAs in cancer
5.Roles of CAs in other diseases
6.Young researchers
7.Poster sessions
Detailed explanations about the location, registration, fees and other details are provided in this website which will be updated periodically.

Main Sessions and Invited Speakers

Introductory plenary lecture:Claudiu T. Supuran, Univ. Florence, IT: [email protected]
What’s new in the carbonic anhydrase field, an update of research from 2009-2012

1.Comparative aspects of new CA families and isozymes (5 speakers)Greg Ferry, Univ. of Pennsylvania, USA: [email protected]
The Iron-Containing Gamma and Beta Carbonic Anhydrases

Robert McKenna, Univ. of Florida, USA: [email protected]
The fine tuning of the alpha class carbonic anhydrases

Didier Zoccola, Centre Scientifique, Monaco, [email protected]
New insights into coral carbonic anhydrases: from physiology to climate change

Fritz Muhlschlegel, Univ. of Kent, UK: [email protected]
A novel pathway regulating the expression of carbonic anhydrases in yeast

Martha Ludwig, Murdoch Univ., Australia: [email protected]
The molecular evolution of plant beta carbonic anhydrases

2.Regulation of expression/function of CA isoforms (4 speakers)Jaromir Pastorek, Slovak Academy of Sciences, SK: [email protected]
Regulation of the CA IX function by phosphorylation in response to physiological stimuli

Jochen Deitmer, Univ. of Kaiserslautern, DE: [email protected]
The role of different carbonic anhydrases for bicarbonate/CO2 transport across cell membranes

Pawel Swietach, Univ. of Oxford, UK: [email protected]
Role of CO2/HCO3- buffer and carbonic anhydrases in pH regulation in 3-D tumour cell growths

Gerolf Gross, Univ. of Hannover, DE: [email protected]
Interaction of carbonic anhydrases and CO2 channels in cellular CO2 uptake and release

3.CAs as drug and diagnostic targets (7 speakers)Dario Neri, ETH, CH: [email protected]
New CAIX ligands from DNA-encoded chemical libraries: isolation and pharmaceutical applications

Jean-Yves Winum, Univ. of Montpellier, FR: [email protected]
Modulation of Carbonic anhydrase Activity with Nanoparticles

Sally-Ann Poulsen, Griffith Univ., Australia: [email protected]
New small molecule inhibitors of carbonic anhydrases

Sebastien Thibaudeau, Univ. Poitiers, FR: [email protected]
Superacid chemistry: a new synthetic tool in the design of carbonic anhydrase inhibitors

Marc Illies, Temple Univ., USA: [email protected]
Pyridinium group – a versatile moiety for targeting carbonic anhydrase isozymes

Andrea Scozzafava, Univ. of Florence, IT: [email protected]
Drug design of antiglaucoma CAIs

Giuseppina De Simone, CNR, IT: [email protected]
Multiple binding modes of inhibitors to carbonic anhydrases

4.Roles of CAs in cancer (7 speakers)Adrian Harris, Univ. of Oxford, UK: [email protected]
Prognostic and therapeutic implications of CA9 expression, interactions with HDAC inhibitors and bicarbonate transport inhibitors

Massimiliano Bonafe, Univ. of Bologna, IT: [email protected]
Post-transcriptional regulation of Carbonic Anhydrase IX in the hypoxic cancer stem cell niche

Shoukat Dedhar, British Columbia Cancer Research Center ( BCCRC) and University of British Columbia ( UBC), Canada: [email protected]
Depletion of Cancer Stem Cells by Targeting Carbonic Anhydrase IX

Silvia Pastorekova, Slovak Academy of Sciences, SK: [email protected]
CA IX as an active component of tumor phenotype and its cross-talk with oncogenic pathways

Kaye Williams, Univ. of Manchester, UK: [email protected]
Therapeutic opportunities in targeting tumour-associated CA9 expression

Jan Lakota, National Cancer Institute, Bratislava, SK: [email protected]
The role of CA I in spontaneous tumor regression.

Harun Said, UNiv. of Wurzburg, DE: [email protected], [email protected]
Functional and regulatory role of Sulfonamide deravitive compounds of Different classes on the expression of Carbonic anhydrase 9 (CA9) in Human Brain Cancer Diseases

5.Roles of CAs in other diseases (6 speakers)Seppo Parkkila, Tampere Univ., FI: [email protected]
Role of CARPs: Novel information from zebrafish models.

EriK R. Swenson, Washington Univ., USA: [email protected]
Carbonic anhydrase in cardiovascular-pulmonary diseases

William S. Sly, St. Louis Univ., USA: [email protected]
CA V KO mice show us why mice need mitochondrial CAs

Abdul Waheed, St. Louis Univ., USA: [email protected]
Mechanism by which CA IV mutations induce eye disease

Kai Kaila, Univ. of Helsinki, FI: [email protected]
Role of CA7 in the control of neuronal excitability and seizure generation

Shelley Minteer, Utah Univ., USA: [email protected] , [email protected]
Mitochondrial electrodes for electrochemically assaying carbonic anhydrase

6.Young researchers (8 speakers)Ozlen Guzel, Istanbul Univ., TR [email protected]
Synthesis and Pharmacological Evaluation of New Series of 3-Phenyl-1H-indole-5-Sulfonamides as Promising Carbonic Anhydrase Inhibitors
Ozen Ozensoy Guler, Yildirim Beyazit Univ., TR [email protected]
Saccharomyces cerevisiae β-carbonic anhydrase: inhibition and activation studies

Deniz Ekinci, Ondokuz Mayıs Univ., TR [email protected]
‘Fish carbonic anhydrases and inhibitors’

Ludwig Dubois, Maastricht Univ., NL

Fabrizio Carta, Univ. of Florence, IT [email protected]
Dithiocarbamates: a novel class of Carbonic Anhydrase inhibitors

Eliska Svastova, Slovak Academy of Sciences

Bogdan Iorga, CNRS, Gif-sur-Yvette, FR [email protected]
New developments in carbonic anhydrase molecular modeling

Murat Kucuk [email protected]
Carbonic Anhydrase Inhibition by Plant Products – Application of Combined Chromatography-Bioactivity

Zahid Chohan, [email protected]
Metal Chelates as Carbonic Anhydrase (CA) Inhibitors

7.Poster sessions* Participants may attend the congress only with poster presentations. Oral Presentations will be presented by only invited speakers. Participants can be participated maximum 2 posters.
General Information

April 11 – 15, 2012


Please bookmark this website. New information will be added to the web site regularly.


IC Hotel Green Palace, Antalya, Turkey.
Telephone 00 90 242 431 2800
Fax 00 90 242 431 2818
Address Özlü Köyü, Kocaçam Mevkii Kundu 07110, Antalya, Türkiye
Distances Airport: 20 KM 
 IC Hotels Green Palace, member of IC Hotels chain is a five star hotel, located in, Antalya.

Official language of the conference and of correspondance is English

Upon registration, each participant will receive a name badge to be worn at all times during the Congress activities and social events. Invitations to social events will be collected by entry.

A certificate of attendance will be obtained by request during or after the Conference. Please request during or after the Conference. Please contact the Registration Desk upon arrival.

We look forward to see you in Antalya in 2012.

Vice Rector, Ataturk University
Ataturk University Faculty of Science
Department of Biochemistry
25240, Erzurum, Turkey
 Prof.Dr. Claudiu T. Supuran
University of Florence
Dipartimento di Chimica
Laboratorio di Chimica Bioinorganica
Via della Lastruccia, 3, Rm. 188, Polo Scientifico,
50019, Sesto Fiorentino Firenze, Italy